A postdoctoral position is open in our group in the context of a long-term project focused on understanding the molecular bases and therapeutic implications of cellular heterogeneity in pancreatic cancer.
Pancreatic cancer is the deadliest among common cancers and is predicted to become the second cause of cancer deaths in the next decade. The massive loss of lineage fidelity by transformed cells and the ensuing high level of cellular and architectural heterogeneity, result in the generation of a mixed cellular population that includes highly invasive, metastasizing and treatment-resistant cells. A detailed understanding of the molecular and regulatory bases of such complexity is thus the prerequisite to improve current therapies.
The project is based on the use of complementary cutting-edge technologies, including sequencing- and imaging-based spatial transcriptomics as well as advanced cell biology platforms. It involves tight interactions with other members of a team working on pancreatic cancer and with the broad community of experimental and computational biologists of the IFOM-IEO Campus.
The applicants should hold a PhD and have expertise in molecular biology and genomics. Enthusiasm for science and research, as well as motivation and willingness to contribute to a dynamic and enjoyable working environment are highly valued qualities in our department.
The Department of Experimental Oncology of IEO belongs to the EU-LIFE alliance for the promotion of science excellence in Europe and is located close to the Milan centre, one of the most dynamic and lively European cities. It hosts more than 250 researchers and advanced technological units.