Tumor immunology

Infiltration by immune cells is a hallmark of several cancer types and in the recent years research has underlined the active role played by the immune system in cancer progression, whose activation often correlates with poor patients prognosis, by enabling clonal survival and drug resistance, which highlighted the potential powerful tool of manipulating the involved cell subtypes to improve cancer patients’ outcome. In this context, our scientists have made major discoveries.

Role of alarmins and neutrophils in carcinogenesis

Identification of a gut vascular barrier

L1 in tumor vasculature