The Cancer Epigenetics Laboratory investigates non-genetic alterations promoting cancer development, with a particular focus on chromatin-based mechanisms operating in solid cancers. Recent studies by our group have uncovered unexpected disease mechanisms, with direct implications for disease management (Torres et al., Science 2016, Loukas et al., Cancer Cell, 2023, Monserrat et al. Nature Cell Biology 2021). We have also used computational methods and AI approaches to gain insights into CRISPR-mediated genome editing (Chakrabarti et al, Molecular Cell 2019). Our research combines genomics, CRISPR-based genetics, microscopy and in vivo/ex vivo functional assays to uncover new biology through the study of altered cellular states in cancer, as well as to identify associated vulnerabilities that can be exploited to interfere with the disease.
We are looking for two enthusiastic scientists with a degree in a life science/computational discipline to join the IEO group. The specific project will be decided based on previous experience and interests of the successful candidates.
Qualifications:
- Wet: a degree in a life science discipline and previous experience with molecular and cellular biology.
- Dry: a degree in bioinformatics/computer science, with experience either in the analysis of NGS datasets or machine learning approaches, or a degree in life sciences with previous experience in bioinformatics.
Competencies: Proficient English, independent working capacity in line with career stage, excellent organizational and collaborative skills. Candidates are expected to be self-motivated research scientists driven by scientific curiosity and proactive in developing their research projects.
Ph.D. training: Post-graduate applicants will have the possibility and will be encouraged to apply to the selection (September 2026) of the European School of Molecular Medicine SEMM (www.semm.it) to join our Ph.D. program in Molecular Medicine.
Salary: A competitive salary will be offered depending on experience and qualifications.
Processing of Personal Data:
The personal data, compulsorily provided, will be processed in compliance with Legislative Decree no. 101 of 10 August 2018, which adapts the Personal Data Protection Code (Legislative Decree no. 196 of 30 June 2003) to the provisions of Regulation (EU) 2016/679, and only for the fulfilments related to this procedure and for those consequent to the possible establishment of the working relationship, according to what is also provided for in the privacy policy, which must be accepted by each candidate at the time of sending his/her application.
Equal opportunities:
This notice is issued in compliance with equal opportunities between men and women for access to employment (L. 903/77) and economic treatment, pursuant to Legislative Decree no. 198/2006.
Posted on 2nd February 2026