Patent Portfolio

IEO PATENT PORTFOLIO

Therapeutic Small Molecules

Molecules for use in the treatment of viral infections

Epigenetic drugs for use in the treatment and/or prevention of a viral infection and method to screen a therapeutic treatment of a viral infection

Application n.

IT-102020000007873

Priority Date

14/04/2020

Main Inventor(s)

Luca Mazzarella

Saverio Minucci

Pier Giuseppe Pelicci

Status

Available for partnering

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Hect E3 ligase NEDD4 inhibitors and uses thereof

New E3 ubiquitin-ligase NEDD4 inhibitor molecules and their use for the treatment of oncological and infectious pathologies

Application n.

PCT/EP2020/065372

Priority Date

03/06/2019

Main Inventor(s)

Sebastiano Pasqualato

Status

For more information

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Therapy and diagnosis of disease characterized by alterations in the DNA damage response

Activators of PP2A phosphatase, their use for the treatment of oncological pathologies and method to identify eligible patients for PP2A activators-based therapy.

Application n.

PCT/EP2018/063257

Priority Date

19/05/2017

Main Inventor(s)

Saverio Minucci

Status

Available for partnering

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Reprogramming-based models of neurodevelopmental disorders and uses thereof  

Neuronal cell models based on reprogrammed stem cells from patients with autism spectrum disorders, methods of obtaining them and use of LSD1 inhibitors for their treatment.

Application n.

PCT/EP2015/077659

Priority Date

26/11/2014

Main Inventor(s)

Giuseppe Testa 

Status

Available for partnering

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New LSD1 inhibitor molecules in oncology (7 patent families)

New small molecules inhibiting LSD1 enzyme for the treatment of oncological diseases alone or in combination with other therapeutic agents

Application n.

PCT/EP2011/055990

PCT/EP2013/075409

PCT/EP2015/062037

PCT/IB2015/001953

PCT/EP2017/062009

PCT/EP2018/060637

 

PCT/EP2018/072319

Priority Date

20/04/2010

05/12/2012

30/05/2014

05/09/2014

18/05/2016

26/04/2017

 

18/08/2017

Main Inventor(s)

Saverio Minucci

Mario Varasi

Mario Varasi

Mario Varasi

Mario Varasi

Saverio Minucci       

Pier Giuseppe Pelicci

Mario Varasi

 

 

Biologicals

Antibodies anti-tumor associated antigens and method for obtaining them

New tumor-specific antibodies, method for obtaining them and their use in the treatment of oncological pathologies.

Application n.

PCT/EP2019/066217

Priority Date

19/06/2018

Main Inventor(s)

Pier Giuseppe Pelicci

Status

Available for partnering

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Postbiotic-based composition for treatment of ocular inflammation  

Metabolic products of Lactobacillus Paracasei for the treatment of conjunctivitis

Application n.

PCT/EP2017/069681

Priority Date

03/08/2016

Main Inventor(s)

Maria Rescigno

Status

Partnered

 

Methods and biomarkers

A novel isoform of the cell-surface adhesion molecule L1 having high angiogenic activity

New soluble isoform of L1 adhesion protein and related diagnostic kit for the detection and monitoring of oncological pathologies

Application n.

IT n. 102018000007726

Priority Date

01/08/2018

Main Inventor(s)

Ugo Cavallaro

Status

Available for partnering

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Use of the expression of specific genes for the prognosis of patients with triple negative breast cancer  

Use of the expression of specific genes for prognostic evaluation in patients with triple negative breast cancer and who have received neoadjuvant chemotherapy

Application n.

PCT/EP2017/066533

Priority Date

01/07/2016

Main Inventor(s)

Giuseppe Curigliano

Status

For more information

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Methods and kits comprising gene signatures for stratifying breast cancer patients

Prognostic molecular signature for the evaluation of risk of relapse in patients with ER positive and HER2 negative breast cancer

Application n.

PCT/EP2017/064937

Priority Date

20/06/2016

Main Inventors

Pier Paolo DI Fiore

Salvatore Pece

Status

Partnered

 

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