The Imaging Unit (IU) supports DEO scientific groups by offering cutting-edge optical imaging platforms and developing tailored imaging protocols and image analysis pipelines as per specific requirements.
More specifically, the IU activity include:
- Conducting mandatory microscope training sessions to facilitate direct access to all IU microscopes
- Providing image analysis support, including integration of machine learning into image analysis
- Offering consulting services for sample preparation in optical microscopy experiments
- Offering direct support and troubleshooting at the microscopes
- Managing departmental imaging reagents
- Teaching (SEMM PhD school and Master in Biomedical Omics of the University of Milan)
Additionally, IU staff actively participates in research collaborations with various research groups
Tools we use:
- image analysis: Fiji/ImageJ, QuPath, ArivisVision 4D, NIS-Elements, Huygens, Python
- data analysis: R, Python
Most Relevant Publications
Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide.
Mol Cell, 2024
Inhibition of the lysine demethylase LSD1 modulates the balance between inflammatory and antiviral responses against coronaviruses.
Sci Signal, 2023
Genes Dev, 2023
Cell Metab, 2023