|Location|| Building 13 |
Floor 2nd, Cluster Franklin
Via Adamello 16, Milano
Andrea Basile graduated in Biological Sciences at the Università degli Studi of Milan, studying the genomic structure of the GATA-1 gene. He next moved to the Istituto di Ricerche Farmacologiche “Mario Negri” (Milan), where he worked as a research associate in Prof. Alberto Mantovani’s group. He was then awarded a fellowship at the Telethon Institute of Genetics and Medicine – Milan, where he contributed to a project aimed at the identification of neurodevelopmental genes. After a stint as a technical consultant at Medway SA, Switzerland, he moved back to academia and obtained a PhD in Molecular Medicine at the Università degli Studi of Milan. In 2006, he became an Associate Professor of Laboratory Medicine at the Università degli Studi of Milan. Since 2008, he has been collaborating with Prof. Pier Paolo Di Fiore's group at the Istituto Europeo di Oncologia (IEO), Milan. His current research interest lies in the evaluation of the role of the tumor suppressor Numb in breast cancer, with a focus on its interaction with pivotal cellular pathways, such as p53/HDM2 signalling, and the identification of novel molecules for cancer treatment.
Most Relevant Publications
A Numb-Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer.
J Cell Biol, 2018
Notch-directed microenvironment reprogramming in myeloma: a single path to multiple outcomes
Notch1 regulates chemotaxis and proliferation by controlling the CC-chemokine receptors 5 and 9 in T cell acute lymphoblastic leukaemia.
J Pathol., 2012