|Location|| Building 13 |
Via Adamello 16, Milano
1984 Medical Doctor, Summa cum laude, University of Perugia, Italy.
1989 Internal Medicine Specialist, Summa cum laude, University of Perugia, Italy. 1994 Ph.D. in Molecular and Cellular Biology, University of Perugia, Italy. 1996- 2004 Staff Scientist, Dpt of Experimental Oncology, IEO, Milan, Italy. 2005-2015 Group Leader, Dpt of Experimental Oncology, IEO, Milan, Italy.
Since 2015- Unit Director, “Biology of Glioblastomas and Brain Metastases and potential therapeutic targets” Dpt of Experimental Oncology, IEO, Milan, Italy. 2013 Associate Professor of Molecular Biology
Scientific Achievements: She cloned the SHC gene (Pelicci G, Cell 1992) and defined the role of Shc proteins in signal transduction from activated tyrosine kinases to Ras (Rozakis-Adcock, Nature 1992). She contributed to the definition of the role of the p66shc splice variant in the control of life-span in mammals (Migliaccio E, Nature 1999).
Current Research: Biology of cancer stem cells focusing on basic and translational cancer research in the fields of brain tumors and brain metastases. Comprehensive molecular characterization of blood extracellular vesicles to develop a reliable liquid biopsy thus leading to personalize the treatment.
Her group combines cell and molecular biology approaches together with next generation sequencing methods and xenograft models.