Luigi Scietti

Luigi Scietti is the coordinator of the Biochemistry and Structural Biology Unit (BSU) at the European Institute of Oncology (IEO) in Milan.

In 2012, after completing his studies in Molecular Biology and Genetics at the University of Pavia (with an experimental thesis in Prof. A. Mattevi’s lab), he moved to Novartis Vaccines (now GSK) in Siena for a PhD in Molecular and Cellular Biology. There, he combined protein microarray technology with biochemistry and biophysics to investigate the molecular mechanisms mediating pathogen recognition and evasion. He then joined the Prof. F. Forneris’ Armenise-Harvard laboratory of structural biology in Pavia in 2016 for a PostDoc. In this lab, he set the grounds for a new research line focusing on collagen modifying enzyme. His research activity yielded (among the others) the first three-dimensional structure of a human collagen lysyl-hydroxylase (LH3). In 2021 he joined IEO as coordinator of the Biochemistry and Structural Biology Unit (BSU).

Luigi’s activities allowed the set-up of the CryoEM pipelines at IEO and are now focussed in importing and implementing the latest technologies in protein production and integrative protein structure determination.